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In vitro deposition of Ca-P nanoparticles on air jet spinning Nylon 6 nanofibers scaffold for bone tissue engineering

Microporous, non-woven nylon 6 (N6) scaffolds were prepared with an air jet spinning (AJS) approach. In this process, polymer fibers with diameters down to the nanometer range (nanofibers) were formed by subjecting a fluid jet to high pressure air. The effects of the solution conditions on the morph...

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Autores Principales: Abdal-Hay, A, Vanegas Peralta, Pablo Fernando
Formato: Artículos
Publicado: ELSEVIER 2018
Materias:
Air jet spinning
Bone tissue engineering
Electrospinning
Nylon 6
Acceso en línea:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84901304005&doi=10.1016%2fj.apsusc.2014.03.161&partnerID=40&md5=eb3f266cc89930e898f104aa2ed9c8f9
http://dspace.ucuenca.edu.ec/handle/123456789/22033
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spelling oai:localhost:123456789-220332018-02-17T11:27:01Z In vitro deposition of Ca-P nanoparticles on air jet spinning Nylon 6 nanofibers scaffold for bone tissue engineering Abdal-Hay, A Vanegas Peralta, Pablo Fernando Air jet spinning Bone tissue engineering Electrospinning Nylon 6 Microporous, non-woven nylon 6 (N6) scaffolds were prepared with an air jet spinning (AJS) approach. In this process, polymer fibers with diameters down to the nanometer range (nanofibers) were formed by subjecting a fluid jet to high pressure air. The effects of the solution conditions on the morphological appearance and average diameter of the as-spun N6 fibers and crystal structure were investigated. The morphological properties of the AJS membrane mats could easily be tailored by adjusting the concentration of the polymer solution. Solutions at high concentrations were necessary to form well-defined fibers without beads. The production rate (viz. solvent evaporation rate) had the greatest effect on the chain structure conformation of N6. The predominant structure phase of the N6 fibers fabricated by AJS was a thermodynamically stable ?-form while the electrospinning fibers induced the metastable ?-form. AJS significantly enhanced the mechanical properties of the N6 mat. The bone formation ability of AJS fibers was evaluated by incubating the fibers in biomimetic simulated body fluid for 5 and 10 days at 37 °C. Overall, the new AJS approach developed for membrane structures has great potential for the fabrication of hard and soft tissue engineering scaffolds. © 2014 Elsevier B.V. All rights reserved. 2018-01-11T21:21:48Z 2018-01-11T21:21:48Z 2014-07-15 info:eu-repo/semantics/Article 1694332 https://www.scopus.com/inward/record.uri?eid=2-s2.0-84901304005&doi=10.1016%2fj.apsusc.2014.03.161&partnerID=40&md5=eb3f266cc89930e898f104aa2ed9c8f9 http://dspace.ucuenca.edu.ec/handle/123456789/22033 10.1016/j.apsusc.2014.03.161 en_US instname:Universidad de Cuenca reponame:Repositorio Digital de la Universidad de Cuenca info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/3.0/ec/ ELSEVIER Applied Surface Science info:eu-repo/date/embargoEnd/2022-01-01 0:00
institution UCUENCA
collection Repositorio UCUENCA
universidades UCUENCA
language
format Artículos
topic Air jet spinning
Bone tissue engineering
Electrospinning
Nylon 6
spellingShingle Air jet spinning
Bone tissue engineering
Electrospinning
Nylon 6
Abdal-Hay, A
Vanegas Peralta, Pablo Fernando
In vitro deposition of Ca-P nanoparticles on air jet spinning Nylon 6 nanofibers scaffold for bone tissue engineering
description Microporous, non-woven nylon 6 (N6) scaffolds were prepared with an air jet spinning (AJS) approach. In this process, polymer fibers with diameters down to the nanometer range (nanofibers) were formed by subjecting a fluid jet to high pressure air. The effects of the solution conditions on the morphological appearance and average diameter of the as-spun N6 fibers and crystal structure were investigated. The morphological properties of the AJS membrane mats could easily be tailored by adjusting the concentration of the polymer solution. Solutions at high concentrations were necessary to form well-defined fibers without beads. The production rate (viz. solvent evaporation rate) had the greatest effect on the chain structure conformation of N6. The predominant structure phase of the N6 fibers fabricated by AJS was a thermodynamically stable ?-form while the electrospinning fibers induced the metastable ?-form. AJS significantly enhanced the mechanical properties of the N6 mat. The bone formation ability of AJS fibers was evaluated by incubating the fibers in biomimetic simulated body fluid for 5 and 10 days at 37 °C. Overall, the new AJS approach developed for membrane structures has great potential for the fabrication of hard and soft tissue engineering scaffolds. © 2014 Elsevier B.V. All rights reserved.
author Abdal-Hay, A
Vanegas Peralta, Pablo Fernando
author_facet Abdal-Hay, A
Vanegas Peralta, Pablo Fernando
author_sort Abdal-Hay, A
title In vitro deposition of Ca-P nanoparticles on air jet spinning Nylon 6 nanofibers scaffold for bone tissue engineering
title_short In vitro deposition of Ca-P nanoparticles on air jet spinning Nylon 6 nanofibers scaffold for bone tissue engineering
title_full In vitro deposition of Ca-P nanoparticles on air jet spinning Nylon 6 nanofibers scaffold for bone tissue engineering
title_fullStr In vitro deposition of Ca-P nanoparticles on air jet spinning Nylon 6 nanofibers scaffold for bone tissue engineering
title_full_unstemmed In vitro deposition of Ca-P nanoparticles on air jet spinning Nylon 6 nanofibers scaffold for bone tissue engineering
title_sort in vitro deposition of ca-p nanoparticles on air jet spinning nylon 6 nanofibers scaffold for bone tissue engineering
publisher ELSEVIER
publishDate 2018
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-84901304005&doi=10.1016%2fj.apsusc.2014.03.161&partnerID=40&md5=eb3f266cc89930e898f104aa2ed9c8f9
http://dspace.ucuenca.edu.ec/handle/123456789/22033
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score 11,871979

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