Novel bone regeneration matrix for next-generation biomaterial using a vertical array of carbonated hydroxyapatite nanoplates coated onto electrospun nylon 6 nanofibers

For the first time, a novel method for nucleation and deposition of vertically arrayed carbonated hydroxyapatite (HA) nanoplates without obvious agglomeration onto the post-electrospun nylon 6 (N6) nanofibers was successfully designed. The technique is based on a simple hydrothermal treatment of the...

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Autor Principal: Salam Hamdy, A
Formato: Artículos
Publicado: ELSEVIER 2018
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Acceso en línea:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84907856467&doi=10.1016%2fj.matlet.2014.09.034&partnerID=40&md5=33d7190adca703172b0cb5f2b3050b18
http://dspace.ucuenca.edu.ec/handle/123456789/29101
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spelling oai:localhost:123456789-291012018-02-17T11:26:33Z Novel bone regeneration matrix for next-generation biomaterial using a vertical array of carbonated hydroxyapatite nanoplates coated onto electrospun nylon 6 nanofibers Salam Hamdy, A Biomaterials Bone-regeneration Electrospun nylon 6 Hydroxyapatite nanoplates Nanofibers Nanostructures For the first time, a novel method for nucleation and deposition of vertically arrayed carbonated hydroxyapatite (HA) nanoplates without obvious agglomeration onto the post-electrospun nylon 6 (N6) nanofibers was successfully designed. The technique is based on a simple hydrothermal treatment of the fabricated N6 mat. The excellent bioactivity of the treated scaffold was confirmed in vitro within MC3T3-E1 osteoblastic cells by significant attachment and in-growth activity on the treated scaffold, and the ability to differentiate into osteoblastic cells with excellent osteogenic potential higher than that of plain nanofibers. Based on this study, the bioactive N6 nanofibers matrix treated with HA nanoplated is regarded as a promising next-generation biomaterial in the bone regeneration field. 2018-01-11T16:47:24Z 2018-01-11T16:47:24Z 2014-12-15 info:eu-repo/semantics/Article 0167577X https://www.scopus.com/inward/record.uri?eid=2-s2.0-84907856467&doi=10.1016%2fj.matlet.2014.09.034&partnerID=40&md5=33d7190adca703172b0cb5f2b3050b18 http://dspace.ucuenca.edu.ec/handle/123456789/29101 10.1016/j.matlet.2014.09.034 en_US instname:Universidad de Cuenca reponame:Repositorio Digital de la Universidad de Cuenca info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by-nc-sa/3.0/ec/ ELSEVIER Materials Letters info:eu-repo/date/embargoEnd/2022-01-01 0:00
institution UCUENCA
collection Repositorio UCUENCA
universidades UCUENCA
language
format Artículos
topic Biomaterials
Bone-regeneration
Electrospun nylon 6
Hydroxyapatite nanoplates
Nanofibers
Nanostructures
spellingShingle Biomaterials
Bone-regeneration
Electrospun nylon 6
Hydroxyapatite nanoplates
Nanofibers
Nanostructures
Salam Hamdy, A
Novel bone regeneration matrix for next-generation biomaterial using a vertical array of carbonated hydroxyapatite nanoplates coated onto electrospun nylon 6 nanofibers
description For the first time, a novel method for nucleation and deposition of vertically arrayed carbonated hydroxyapatite (HA) nanoplates without obvious agglomeration onto the post-electrospun nylon 6 (N6) nanofibers was successfully designed. The technique is based on a simple hydrothermal treatment of the fabricated N6 mat. The excellent bioactivity of the treated scaffold was confirmed in vitro within MC3T3-E1 osteoblastic cells by significant attachment and in-growth activity on the treated scaffold, and the ability to differentiate into osteoblastic cells with excellent osteogenic potential higher than that of plain nanofibers. Based on this study, the bioactive N6 nanofibers matrix treated with HA nanoplated is regarded as a promising next-generation biomaterial in the bone regeneration field.
author Salam Hamdy, A
author_facet Salam Hamdy, A
author_sort Salam Hamdy, A
title Novel bone regeneration matrix for next-generation biomaterial using a vertical array of carbonated hydroxyapatite nanoplates coated onto electrospun nylon 6 nanofibers
title_short Novel bone regeneration matrix for next-generation biomaterial using a vertical array of carbonated hydroxyapatite nanoplates coated onto electrospun nylon 6 nanofibers
title_full Novel bone regeneration matrix for next-generation biomaterial using a vertical array of carbonated hydroxyapatite nanoplates coated onto electrospun nylon 6 nanofibers
title_fullStr Novel bone regeneration matrix for next-generation biomaterial using a vertical array of carbonated hydroxyapatite nanoplates coated onto electrospun nylon 6 nanofibers
title_full_unstemmed Novel bone regeneration matrix for next-generation biomaterial using a vertical array of carbonated hydroxyapatite nanoplates coated onto electrospun nylon 6 nanofibers
title_sort novel bone regeneration matrix for next-generation biomaterial using a vertical array of carbonated hydroxyapatite nanoplates coated onto electrospun nylon 6 nanofibers
publisher ELSEVIER
publishDate 2018
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-84907856467&doi=10.1016%2fj.matlet.2014.09.034&partnerID=40&md5=33d7190adca703172b0cb5f2b3050b18
http://dspace.ucuenca.edu.ec/handle/123456789/29101
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