In Vitro Deposition of Ca-P Nanoparticles on Air Jet Spinning Nylon 6 Nanofibers Scaffold For Bone Tissue Engineering

Microporous, non-woven nylon 6 (N6) scaffolds were prepared with an air jet spinning (AJS) approach. In this process, polymer fibers with diameters down to the nanometer range (nanofibers) were formed by subjecting a fluid jet to high pressure air. The effects of the solution conditions on the morph...

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Main Author: Abdal-hay, Abdalla
Format: Artículos
Language:eng
Published: 2016
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Online Access:http://repositorio.educacionsuperior.gob.ec/handle/28000/2607
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spelling oai:localhost:28000-26072017-04-11T14:54:57Z In Vitro Deposition of Ca-P Nanoparticles on Air Jet Spinning Nylon 6 Nanofibers Scaffold For Bone Tissue Engineering Abdal-hay, Abdalla AIR JET SPINNING NYLON 6 BONE TISSUE ENGINEERING ELECTROSPINNING Microporous, non-woven nylon 6 (N6) scaffolds were prepared with an air jet spinning (AJS) approach. In this process, polymer fibers with diameters down to the nanometer range (nanofibers) were formed by subjecting a fluid jet to high pressure air. The effects of the solution conditions on the morphological appearance and average diameter of the as-spun N6 fibers and crystal structure were investigated. The morphological properties of the AJS membrane mats could easily be tailored by adjusting the concentration of the polymer solution. Solutions at high concentrations were necessary to form well-defined fibers without beads. The production rate (viz. solvent evaporation rate) had the greatest effect on the chain structure conformation of N6. The predominant structure phase of the N6 fibers fabricated by AJS was a thermodynamically stable ?-form while the electrospinning fibers induced the metastable ?-form. AJS significantly enhanced the mechanical properties of the N6 mat. The bone formation ability of AJS fibers was evaluated by incubating the fibers in biomimetic simulated body fluid for 5 and 10 days at 37 ?C. Overall, the new AJS approach developed for membrane structures has great potential for the fabrication of hard and soft tissue engineering scaffolds. Universidad De Cuenca http://www.sciencedirect.com/science/article/pii/S0169433214007120 2016-10-28T19:55:48Z 2016-10-28T19:55:48Z 2014 article Abdal-hay, Abdalla. et al. (2014). In Vitro Deposition of Ca-P Nanoparticles on Air Jet Spinning Nylon 6 Nanofibers Scaffold For Bone Tissue Engineering. Applied Surface Science. Vol 307. pp 69?76. 0169-4332 http://repositorio.educacionsuperior.gob.ec/handle/28000/2607 eng restrictedAccess pp 69?76.
institution SENESCYT
collection Repositorio SENESCYT
biblioteca Biblioteca Senescyt
language eng
format Artículos
topic AIR JET SPINNING
NYLON 6
BONE TISSUE ENGINEERING
ELECTROSPINNING
spellingShingle AIR JET SPINNING
NYLON 6
BONE TISSUE ENGINEERING
ELECTROSPINNING
Abdal-hay, Abdalla
In Vitro Deposition of Ca-P Nanoparticles on Air Jet Spinning Nylon 6 Nanofibers Scaffold For Bone Tissue Engineering
description Microporous, non-woven nylon 6 (N6) scaffolds were prepared with an air jet spinning (AJS) approach. In this process, polymer fibers with diameters down to the nanometer range (nanofibers) were formed by subjecting a fluid jet to high pressure air. The effects of the solution conditions on the morphological appearance and average diameter of the as-spun N6 fibers and crystal structure were investigated. The morphological properties of the AJS membrane mats could easily be tailored by adjusting the concentration of the polymer solution. Solutions at high concentrations were necessary to form well-defined fibers without beads. The production rate (viz. solvent evaporation rate) had the greatest effect on the chain structure conformation of N6. The predominant structure phase of the N6 fibers fabricated by AJS was a thermodynamically stable ?-form while the electrospinning fibers induced the metastable ?-form. AJS significantly enhanced the mechanical properties of the N6 mat. The bone formation ability of AJS fibers was evaluated by incubating the fibers in biomimetic simulated body fluid for 5 and 10 days at 37 ?C. Overall, the new AJS approach developed for membrane structures has great potential for the fabrication of hard and soft tissue engineering scaffolds.
author Abdal-hay, Abdalla
author_facet Abdal-hay, Abdalla
author_sort Abdal-hay, Abdalla
title In Vitro Deposition of Ca-P Nanoparticles on Air Jet Spinning Nylon 6 Nanofibers Scaffold For Bone Tissue Engineering
title_short In Vitro Deposition of Ca-P Nanoparticles on Air Jet Spinning Nylon 6 Nanofibers Scaffold For Bone Tissue Engineering
title_full In Vitro Deposition of Ca-P Nanoparticles on Air Jet Spinning Nylon 6 Nanofibers Scaffold For Bone Tissue Engineering
title_fullStr In Vitro Deposition of Ca-P Nanoparticles on Air Jet Spinning Nylon 6 Nanofibers Scaffold For Bone Tissue Engineering
title_full_unstemmed In Vitro Deposition of Ca-P Nanoparticles on Air Jet Spinning Nylon 6 Nanofibers Scaffold For Bone Tissue Engineering
title_sort in vitro deposition of ca-p nanoparticles on air jet spinning nylon 6 nanofibers scaffold for bone tissue engineering
publishDate 2016
url http://repositorio.educacionsuperior.gob.ec/handle/28000/2607
_version_ 1634995073014824960
score 11,871979